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House member buys before a drug-trial update

Buy Lab Coats & Lawmakers · ClinicalTrials.gov events

This looks for stocks that may rise. It flags a drug or biotech company when a clinical trial update lands and a U.S. House member also bought that same stock in the days just before. Pairing a trial event with a lawmaker's purchase is meant to be a double sign of confidence. Heads up: most of this came from a single recent year, so it may not repeat.

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House member buys before a drug-trial update vertical poster. This looks for stocks that may rise. It flags a drug or biotech company when a clinical trial update lands and a U.S. House member also bought that same stock in the days just before. Pairing a trial event with a lawmaker's purchase is meant to be a double sign of confidence. Heads up: most of this came from a single recent year, so it may not repeat.House member buys before a drug-trial update landscape card. This looks for stocks that may rise. It flags a drug or biotech company when a clinical trial update lands and a U.S. House member also bought that same stock in the days just before. Pairing a trial event with a lawmaker's purchase is meant to be a double sign of confidence. Heads up: most of this came from a single recent year, so it may not repeat.

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Updated Oct 17 · 1 feed behind: ClinicalTrials.gov events, 1 day · Every feed →

On this page

How the test works

The planned holding period in these tests is 3 months (90 days), from opening to closing an idea.

  1. Buy it when it fires

    At the next trading day’s close after the record posts — the first price anyone could have had.

  2. Hold 3 months

    The same hold for every idea — no stop, no target — so nothing flatters the numbers.

  3. Sell 3 months later

    At the next available trading close on or after the end of the hold, whatever the price.

Every number on this page uses this sell rule — the other sell rules we tested are under “The full test results and the math” below.

How it did in past tests

Collecting forward evidence — past tests passed; new trades pending

Publication check: Collecting forward results

Not passed yet — 3 of 16 checks:

  • It needs at least 20 finished trades on 10 separate days after the rule was frozen.
  • Some of those new trades are still open; each has to finish its full hold.
  • Those new trades then have to beat similar stocks after costs, by more than luck across every rule we tried.

Passed — the other 13: Current calculation · Public disclosure dates · Complete finished trades · Every trade compared · Every trade priced · Enough separate trading days · Positive edge after costs · Survives without the best year · Survives without the best three stocks · Survives higher costs · Rule frozen before the test · Rules tried alongside it counted · First new signals set aside.

Tested exit: 3-month hold. Historical results alone do not approve a rule for publication. New event tests include an estimated 0.20 percentage point round-trip trading cost, with a 0.50-point stress check.

New trades so far: 0 finished, across — separate days after the rule was frozen.

0 signals set aside across 0 disclosure days; 0 still need complete results. Missing results stay in the count.

Average difference in past tests+2.9 percentage pointsagainst similar stocks, over 3 months

Left: did worse · right: did better. Zero matches the comparison. pp = percentage points; the scale adjusts to include the result.

In past tests, each idea returned
+5.4%
on average after 3 months · 196 tries
Similar stocks returned
+2.5%
this did 2.9 percentage points better
Made money in
146 of 196
tries (74%)

196 tries finished the 3-month test · 10 still open · 298 signals ever

Past results don't predict future ones.

Similar stocks means the index fund for each idea's sector — or the S&P 500 when we can't place its sector.

How it did against similar stocks2.9 percentage points better than similar stocks — over 3 months
Range for the average (95%)+0.6 pp to +5.3 pp vs similar stocks — the range the average probably falls in, not a best-to-worst case
Tested on enough tries?196 tries on 137 separate days ✓ enough
Works in different markets?61% from a single year ✓ spread across years
Spread across many stocks?24% from a single stock ✓ broad
Still works without its biggest winner?+2.3 pp vs similar stocks without LLY ✓ holds up
How we grade →

The 5 newest of 196 finished ideas: 1 of 5 beat similar stocks — one block each, newest first

  1. LLY · Jul 9, 2026 · Return −2.4% · −6.9 pp vs similar stocks
  2. JNJ · Jul 7, 2026 · Return −5.1% · −7.3 pp vs similar stocks
  3. PFE · May 15, 2026 · Return +7.5% · −9.1 pp vs similar stocks
  4. LLY · May 14, 2026 · Return +21.2% · +5.8 pp vs similar stocks
  5. AMGN · Apr 23, 2026 · Return +5.6% · −3.9 pp vs similar stocks

did betterdid worseno comparison

LLY · Jul 9, 2026 · Return −2.4% · −6.9 pp vs similar stocks

Inspect all 5 displayed outcomes

pp = percentage points above or below the comparable stock return.

  1. LLY · Jul 9, 2026 · Return −2.4% · −6.9 pp vs similar stocks
  2. JNJ · Jul 7, 2026 · Return −5.1% · −7.3 pp vs similar stocks
  3. PFE · May 15, 2026 · Return +7.5% · −9.1 pp vs similar stocks
  4. LLY · May 14, 2026 · Return +21.2% · +5.8 pp vs similar stocks
  5. AMGN · Apr 23, 2026 · Return +5.6% · −3.9 pp vs similar stocks

Ideas for the week of Oct 12

This week's list isn't set yet — it's set on the first fresh data of the week of Oct 19.

That week's 1 idea from this rule
Members see the stocks and their weights. Weeks older than 90 days are free for everyone — pick one below.
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See the newest free week — week of Jul 13 →

Every idea

Results under the 3-month hold · 10 still open · 196 finished · each idea's sell day is 3 months after it fired · an open idea shows its result so far.

LLYFinished
Final return
−2.4%
vs similar stocks
−6.9 pp
Dates & source
Fired
Jul 9, 2026
Exit date
Oct 7, 2026
JNJFinished
Final return
−5.1%
vs similar stocks
−7.3 pp
Dates & source
Fired
Jul 7, 2026
Exit date
Oct 5, 2026
PFEFinished
Final return
+7.5%
vs similar stocks
−9.1 pp
Dates & source
Fired
May 15, 2026
Exit date
Aug 13, 2026
LLYFinished
Final return
+21.2%
vs similar stocks
+5.8 pp
Dates & source
Fired
May 14, 2026
Exit date
Aug 12, 2026
AMGNFinished
Final return
+5.6%
vs similar stocks
−3.9 pp
Dates & source
Fired
Apr 23, 2026
Exit date
Jul 22, 2026
StockFiredStatusSell dayResultvs similar stocks (pp)
LLYJul 9, 2026FinishedOct 7, 2026−2.4%−6.9 pp
JNJJul 7, 2026FinishedOct 5, 2026−5.1%−7.3 pp
PFEMay 15, 2026FinishedAug 13, 2026+7.5%−9.1 pp
LLYMay 14, 2026FinishedAug 12, 2026+21.2%+5.8 pp
AMGNApr 23, 2026FinishedJul 22, 2026+5.6%−3.9 pp

pp = percentage points: the return minus the comparable-stock return. A dash means the comparison is unavailable.

Showing 5 of 206 ideas

201 more ideas, each with its result
Members see every idea this rule fired, open and finished, under any of the sell rules we tested — and can download them.
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The full test results and the math

pp means percentage points: the difference between two returns. Actual returns are shown in %.

Average result (3 months)
+5.4%
range for the average (95%): +2.9% to +8.4%
Edge over similar stocks
+2.9 pp
range for the average (95%): +0.6 pp to +5.3 pp

Held a year instead: +22.7% on average (141 tries).

Steadiness (Sharpe ratio) 0.88 — solid: how even the results were from one try to the next.

Every sell rule we tested

Every sell rule we tested, side by side, comes with membership.

Risk and style checks

  • After style factors (market, size, value, momentum…) the edge is +2.1 pp instead of +2.9 pp — part of the edge is those tilts — the real edge is smaller. Tilts: Value +1.05 · Investment −0.62 · Momentum −0.57 · R² 0.19.
  • The stocks it picked trade a median $984M a day; 0% of its ideas were in thin stocks (under $2M a day).
  • At one percent of that volume a trade is about $9.8M; with 10 ideas open now, an equal-weight book is about $98.4M.
  • The edge by market fear on the day it fired (the VIX): calm +2.4 pp (32 tries) · normal +3.0 pp (150 tries) · stressed +2.9 pp (14 tries).

How we test and grade every rule →