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SEPN · Septerna, Inc.

Healthcare · +6.7% on Oct 27

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Updated Oct 29 · 6 feeds behind: Congress trades, 12 days, and 5 more · Every feed →

On this page

The market view

Price chart

The interactive SEPN chart (by TradingView) loads here.

Our take

4 rules fired on SEPN

In short: none of these rules has solid or some evidence yet, so they show no clear lean on SEPN.

How each did in past tests, against similar stocks over 3 months. Past results don't predict future ones.

All 4 rules
The 0–100 score for SEPN, and which of these rules are open on it right now
Members see one number for how strongly these rules agree on SEPN, and the day each rule fired. Better-tested rules count more, and so do different kinds of filings that point the same way.
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Compare with this company’s history

Is disclosure activity unusual?

See how many different insiders or members of Congress reported purchases or sales of SEPN. Each bar covers 28 days, by disclosure date. Several trades by one person count once in each group and period.

Latest period: Oct 1, 2026–Oct 28, 2026 · UTC dates · today is excluded

Insider sales

Short history

Only 3 earlier periods are on file to compare with. We need at least 6 full periods before calling a count unusual.

Latest 28 days
1
Earlier median
2
Earlier range
1–12
Distinct filers per 28 daysScale: 0–12
Oct 30, 2025Oct 28, 2026
Earlier periodsLatest 28 daysEarlier median 2Limited or missing history

Who appears in the latest period?

Up to three filers; one example disclosure each.

Inspect this period’s filings

The history behind this view

First stored company disclosure: Jun 16, 2026. Newest disclosure across this feed: Oct 27, 2026.

Earlier periods in the comparison: 3. Outlined periods are missing data, so they are left out of the comparison. The chart scale changes with the category.

Exact counts, dates and filings for all four categories
Insider purchases · Short history

Only 3 earlier periods are on file to compare with. We need at least 6 full periods before calling a count unusual. Earlier median: 0; range: 0–0.

Insider purchases: distinct filers in stored disclosures
Period and filingsFilersHistory
Oct 30, 2025–Nov 26, 2025—Unavailable
Nov 27, 2025–Dec 24, 2025—Unavailable
Dec 25, 2025–Jan 21, 2026—Unavailable
Jan 22, 2026–Feb 18, 2026—Unavailable
Feb 19, 2026–Mar 18, 2026—Unavailable
Mar 19, 2026–Apr 15, 2026—Unavailable
Apr 16, 2026–May 13, 2026—Unavailable
May 14, 2026–Jun 10, 2026—Unavailable
Jun 11, 2026–Jul 8, 20260Partial; excluded
Jul 9, 2026–Aug 5, 20260Within stored history
Aug 6, 2026–Sep 2, 20260Within stored history
Sep 3, 2026–Sep 30, 20260Within stored history
Oct 1, 2026–Oct 28, 2026Latest period0Within stored history
Insider sales · Short history

Only 3 earlier periods are on file to compare with. We need at least 6 full periods before calling a count unusual. Earlier median: 2; range: 1–12.

Insider sales: distinct filers in stored disclosures
Period and filingsFilersHistory
Oct 30, 2025–Nov 26, 2025—Unavailable
Nov 27, 2025–Dec 24, 2025—Unavailable
Dec 25, 2025–Jan 21, 2026—Unavailable
Jan 22, 2026–Feb 18, 2026—Unavailable
Feb 19, 2026–Mar 18, 2026—Unavailable
Mar 19, 2026–Apr 15, 2026—Unavailable
Apr 16, 2026–May 13, 2026—Unavailable
May 14, 2026–Jun 10, 2026—Unavailable
Jun 11, 2026–Jul 8, 20262Partial; excluded
Jul 9, 2026–Aug 5, 20262Within stored history
Aug 6, 2026–Sep 2, 202612Within stored history
Sep 3, 2026–Sep 30, 20261Within stored history
Oct 1, 2026–Oct 28, 2026Latest period1Within stored history
Congress purchases · Source needs an update

The feed’s newest disclosure is too old for a current comparison. Counts show only the records already stored. Earlier median: —; range: unavailable.

Congress purchases: distinct filers in stored disclosures
Period and filingsFilersHistory
Oct 30, 2025–Nov 26, 2025—Unavailable
Nov 27, 2025–Dec 24, 2025—Unavailable
Dec 25, 2025–Jan 21, 2026—Unavailable
Jan 22, 2026–Feb 18, 2026—Unavailable
Feb 19, 2026–Mar 18, 2026—Unavailable
Mar 19, 2026–Apr 15, 2026—Unavailable
Apr 16, 2026–May 13, 2026—Unavailable
May 14, 2026–Jun 10, 2026—Unavailable
Jun 11, 2026–Jul 8, 2026—Unavailable
Jul 9, 2026–Aug 5, 2026—Unavailable
Aug 6, 2026–Sep 2, 2026—Unavailable
Sep 3, 2026–Sep 30, 2026—Unavailable
Oct 1, 2026–Oct 28, 2026Latest period—Unavailable
Congress sales · Source needs an update

The feed’s newest disclosure is too old for a current comparison. Counts show only the records already stored. Earlier median: —; range: unavailable.

Congress sales: distinct filers in stored disclosures
Period and filingsFilersHistory
Oct 30, 2025–Nov 26, 2025—Unavailable
Nov 27, 2025–Dec 24, 2025—Unavailable
Dec 25, 2025–Jan 21, 2026—Unavailable
Jan 22, 2026–Feb 18, 2026—Unavailable
Feb 19, 2026–Mar 18, 2026—Unavailable
Mar 19, 2026–Apr 15, 2026—Unavailable
Apr 16, 2026–May 13, 2026—Unavailable
May 14, 2026–Jun 10, 2026—Unavailable
Jun 11, 2026–Jul 8, 2026—Unavailable
Jul 9, 2026–Aug 5, 2026—Unavailable
Aug 6, 2026–Sep 2, 2026—Unavailable
Sep 3, 2026–Sep 30, 2026—Unavailable
Oct 1, 2026–Oct 28, 2026Latest period—Unavailable
How to read this comparison

The median is the middle count in up to 12 earlier, non-overlapping 28-day periods; the range runs from the smallest to the largest count. The latest period is excluded from both. A comparison needs at least 6 earlier periods, including 3 with activity. The feed’s latest disclosure must be within 7 days of the current period’s end. This freshness check does not verify complete collection.

Insiders include individuals and reporting entities; only purchase and sale codes enter this view. Congress counts reporting members, including their disclosed family transactions. The same filer can appear in purchases and sales, so these categories should not be added into a net count.

These are stored disclosures, not a complete measure of trading. Reporting delays and collection gaps can change the comparison. More activity does not identify a motive or predict a stock’s return.

Company timeline

What has been happening?

May 1, 2026–Oct 27, 2026. Select a month in a category to inspect its records.

Company filings

Insiders

Owners & lobbying

Insiders · Oct 2026

  1. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Oct 15, 2026

  2. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Oct 15, 2026

  3. Filed
  4. Filed
All 36 records in this snapshot
  1. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Oct 15, 2026

  2. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Oct 15, 2026

  3. Filed
  4. Filed
  5. Disclosed
    Daniel D. Long · Sale

    Transaction dated Sep 1, 2026

  6. Filed
  7. Filed
  8. Filed
  9. Disclosed
    Peter Kolchinsky · Sale

    Transaction dated Aug 12, 2026

  10. Disclosed
    RA Capital Healthcare Fund LP · Sale

    Transaction dated Aug 12, 2026

  11. Filed
  12. Disclosed
    Ra Capital Management, L.P. · Sale

    Transaction dated Aug 12, 2026

  13. Disclosed
    RA Capital Nexus Fund III, L.P. · Sale

    Transaction dated Aug 12, 2026

  14. Disclosed
    Rajeev M. Shah · Sale

    Transaction dated Aug 12, 2026

  15. Disclosed
    Third Rock Ventures GP V, LP · Sale

    Transaction dated Aug 12, 2026

  16. Disclosed
    Third Rock Ventures GP V, LP · Sale

    Transaction dated Aug 12, 2026

  17. Disclosed
    Third Rock Ventures GP VI, L.P. · Sale

    Transaction dated Aug 12, 2026

  18. Disclosed
    Third Rock Ventures GP VI, L.P. · Sale

    Transaction dated Aug 12, 2026

  19. Disclosed
    Third Rock Ventures V, L.P. · Sale

    Transaction dated Aug 12, 2026

  20. Disclosed
    Third Rock Ventures V, L.P. · Sale

    Transaction dated Aug 12, 2026

  21. Disclosed
    Third Rock Ventures VI, L.P. · Sale

    Transaction dated Aug 12, 2026

  22. Disclosed
    Third Rock Ventures VI, L.P. · Sale

    Transaction dated Aug 12, 2026

  23. Disclosed
    Trv GP V, LLC · Sale

    Transaction dated Aug 12, 2026

  24. Disclosed
    Trv GP V, LLC · Sale

    Transaction dated Aug 12, 2026

  25. Disclosed
    Trv GP Vi, LLC · Sale

    Transaction dated Aug 12, 2026

  26. Disclosed
    Trv GP Vi, LLC · Sale

    Transaction dated Aug 12, 2026

  27. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Aug 11, 2026

  28. Filed
  29. Filed
  30. Filed
  31. Filed
  32. Filed
  33. Disclosed
    Daniel D. Long · Sale

    Transaction dated Aug 3, 2026

  34. Disclosed
    Daniel D. Long · Sale

    Transaction dated Aug 3, 2026

  35. Disclosed
    Elizabeth Bhatt · Sale

    Transaction dated Jul 15, 2026

  36. Disclosed
    Daniel D. Long · Sale

    Transaction dated Jul 1, 2026

Month counts include every record on file. The lists show the newest records on this page. A dash means none on file that month. Trades use disclosure dates; contract dates follow the source record. Nearby events do not establish the cause of a price move.

Who's buying and selling · last 90 days

Congress

No Congress trades on SEPN disclosed in the last 90 days.

See every Congress trade on SEPN →

Company insiders

0 buys · 15 sells (23 filed lots) · $205M sold

  1. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$40.3Kdisclosed Oct 19 · filed 4 days after the trade
  2. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$109Kdisclosed Oct 19 · filed 4 days after the trade
  3. ▼ SELLDaniel D. Long SVP, Drug DiscoverySEPN Septerna, Inc.$126Kdisclosed Sep 3 · filed 2 days after the trade
  4. ▼ SELLTrv GP V, LLC 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  5. ▼ SELLThird Rock Ventures V, L.P. 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  6. ▼ SELLThird Rock Ventures GP V, LP 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  7. ▼ SELLTrv GP Vi, LLC 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  8. ▼ SELLRajeev M. Shah DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  9. ▼ SELLThird Rock Ventures V, L.P. 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  10. ▼ SELLThird Rock Ventures VI, L.P. 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
See every insider trade on SEPN →

Big holders (Schedule 13D / 13G): 1 filing in the last 90 days · newest: Ra Capital Management, L.P. (13D amendment), Aug 14, 2026 ↗

Filings & events

Company filings (8-K) 33

Events the company must report to the SEC within days — results, deals, departures, restatements.

What it files 8-Ks about

  • Shared information with investors · item 7.018
  • Quarterly or yearly results · item 2.025
  • Other events · item 8.013
  • Shareholder vote results · item 5.072
  • Directors or officers joined, left or got new pay · item 5.022

Filing red flags 1

Warning signs in the company's own SEC filings — going-concern doubts, control weaknesses, staff comment letters, late filings, restatements, Wells notices, clinical holds, dividend cuts.

Planned insider sales (Form 144) 15

Notices insiders file before they sell certain shares, such as ones they got straight from the company.

6 in the last 90 days · 15 notices on file

The notices on file don't give the sale's size; each sale shows up under company insiders once it is reported.

5% owners (13D / 13G) 3

Investors who reported owning 5% or more — 13D for owners who may push for changes, 13G for owners who just hold.

Push for changes, or just hold?

  • 13D, may push for changes: 1 filing
  • 13G, just holds: 2 filings

Filed by Ra Capital Management, L.P. · Driehaus Capital Management LLC · Third Rock Ventures V, L.P.

Biggest named funds (13F)

The largest SEPN holdings among the well-known funds whose quarterly 13F filings we read — opens here.

Every disclosed trade on SEPN

  1. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$40.3Kdisclosed Oct 19 · filed 4 days after the trade
  2. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$109Kdisclosed Oct 19 · filed 4 days after the trade
  3. ▼ SELLDaniel D. Long SVP, Drug DiscoverySEPN Septerna, Inc.$126Kdisclosed Sep 3 · filed 2 days after the trade
  4. ▼ SELLTrv GP V, LLC 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  5. ▼ SELLThird Rock Ventures V, L.P. 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  6. ▼ SELLThird Rock Ventures GP V, LP 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  7. ▼ SELLTrv GP Vi, LLC 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  8. ▼ SELLRajeev M. Shah DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  9. ▼ SELLThird Rock Ventures V, L.P. 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  10. ▼ SELLThird Rock Ventures VI, L.P. 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  11. ▼ SELLThird Rock Ventures VI, L.P. 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  12. ▼ SELLRa Capital Management, L.P. DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  13. ▼ SELLTrv GP V, LLC 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  14. ▼ SELLThird Rock Ventures GP V, LP 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  15. ▼ SELLThird Rock Ventures GP VI, L.P. 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  16. ▼ SELLPeter Kolchinsky DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  17. ▼ SELLRA Capital Nexus Fund III, L.P. DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  18. ▼ SELLRA Capital Healthcare Fund LP DirectorSEPN Septerna, Inc.$31.7Mdisclosed Aug 14 · filed 2 days after the trade
  19. ▼ SELLTrv GP Vi, LLC 10% ownerSEPN Septerna, Inc.$7.2Kdisclosed Aug 14 · filed 2 days after the trade
  20. ▼ SELLThird Rock Ventures GP VI, L.P. 10% ownerSEPN Septerna, Inc.$7.4Mdisclosed Aug 14 · filed 2 days after the trade
  21. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$1.1Mdisclosed Aug 13 · filed 2 days after the trade
  22. ▼ SELLDaniel D. Long SVP, Drug DiscoverySEPN Septerna, Inc.$34Kdisclosed Aug 5 · filed 2 days after the trade
  23. ▼ SELLDaniel D. Long SVP, Drug DiscoverySEPN Septerna, Inc.$80.9Kdisclosed Aug 5 · filed 2 days after the trade
  24. ▼ SELLElizabeth Bhatt President and COOSEPN Septerna, Inc.$136Kdisclosed Jul 17 · filed 2 days after the trade
  25. ▼ SELLDaniel D. Long SVP, Drug DiscoverySEPN Septerna, Inc.$42.9Kdisclosed Jul 2 · filed 1 day after the trade
See all 30 trades on SEPN →
People & votes

Which members of Congress traded SEPN, sponsored bills that touch it and voted on them — opens here.